A strategy for the reversed-phase chromatographic purification of solid-phase-synthesized peptides is described and illustrated by the synthesis of a 23-mer model peptide; the target peptide is distinguished from terminated by-products by the attachment of a hydrophobic probe to the resin-bound peptide.
C. García-Echeverría, J. Chem. Soc., Chem. Commun., 1995, 779 DOI: 10.1039/C39950000779
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