Issue 12, 1994

Azasulfonamidopeptides as peptide bond hydrolysis transition state analogues. Part 1. Synthetic approaches

Abstract

The title compounds, a novel class of peptide analogues in which an α-amino acid residue is replaced by a hydrazine-1, 2-diyl sulfonyl group -NHNRSO2-, are of potential interest as proteinase inhibitors. Synthetic approaches to such compounds and the X-ray molecular structures of two examples (16 and 28) are reported.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1994, 1595-1600

Azasulfonamidopeptides as peptide bond hydrolysis transition state analogues. Part 1. Synthetic approaches

T. J. Cheeseright, A. J. Edwards, D. T. Elmore, J. H. Jones, M. Raissi and E. C. Lewis, J. Chem. Soc., Perkin Trans. 1, 1994, 1595 DOI: 10.1039/P19940001595

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