Katsuki–Sharpless asymmetric epoxidation of alkenylethylene glycols: the origin of inverted stereoselection
Abstract
The Katsuki–Sharpless asymmetric epoxidation of linear and cyclic alkenylethylene glycols has led to a conclusion that the origin of the inverted stereoselection is due to the simultaneous coordination between both hydroxy groups of the glycol substrates and both titanium atoms in the Ti2(tartrate)2 complex.