The β-lactam 4 was linked to the enones 8–10 using a radical reaction mediated by tri-n-butyltin hydride to give the 2,6-disubstituted cyclohexanones 11–16, respectively: 13 was converted into the protected tribactam 18 in two steps.
A. Padova, S. M. Roberts, D. Donati, A. Perboni and T. Rossi, J. Chem. Soc., Chem. Commun., 1994, 441 DOI: 10.1039/C39940000441
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