π-Face differentiation in Michael reaction to the enone group adjacent to the (η-C5H5)Mo(CO)2(π-allyl) fragment: a new approach to the stereoselective synthesis of 2,3,4,5-tetrasubstituted-tetrahydrofuran compounds
Abstract
The stereochemical outcome of the 1,4-addition of organocopper reagents to (η-C5H5)Mo(CO)2[η3-1-(E)-C3H4COCHCHR] compounds has been elucidated; utilization of this reaction for synthesis of 2,3,4,5-tetrasubstituted tetrahydrofuran is demonstrated.