First synthesis of spiro[benzofuran-2,1′-isobenzofuran]-3,3′-dione and its X-ray crystal structure
Abstract
The title compound has been synthesised by selenium dioxide oxidation of 2′-carboxy-2-hydroxy-deoxybenzoin 3 and its structure has been confirmed spectroscopically and by X-ray crystallography. An earlier report of this compound's synthesis is shown to be erroneous. The synthesis of 3-(2-hydroxyphenyl)isoquinolin-1 (2H)-ones from 2′-carboxy-2-hydroxydeoxybenzoin 3 is also described.