Issue 18, 1992

Synthesis of 13C- and 15N-labelled tert-butoxycarbonyl (boc) glycines and glycine amides as precursors and simple models of backbone-labelled peptides

Abstract

Boc-derivatives of the six 13C-labelled glycines with or without 15N have been prepared by a direct approach from the corresponding bromoacetates and three of them converted into 15N-labelled amides by an efficient procedure to give isotopomers with 2–4 adjacent 13C and 15N nuclei; their coupling constants have been recorded.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1992, 1332-1333

Synthesis of 13C- and 15N-labelled tert-butoxycarbonyl (boc) glycines and glycine amides as precursors and simple models of backbone-labelled peptides

L. Grehn, U. Bondesson, T. Pehk and U. Ragnarsson, J. Chem. Soc., Chem. Commun., 1992, 1332 DOI: 10.1039/C39920001332

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