Diastereoselective addition of metal-coordinated and ‘naked’ tri-sec-butylborohydrides to a norephedrine-derived 2-acetyloxazolidine
Abstract
The addition of tri-sec-butylborohydrides to the 2-acetyl-1,3-oxazolidine 1 can be directed with high selectivity to either the Si or the Reπ-carbonyl face under chelating or non-coordinating conditions, respectively.