Treatment of the iodoalanine derived zinc reagent 1 with Knochel's soluble copper salt (CuCN·2LiCl) allows the preparation of a reactive copper reagent 2 which couples in moderate to good yield with allyl halides to give protected unsaturated α-amino acids in a single step from easily available precursors.
M. J. Dunn and R. F. W. Jackson, J. Chem. Soc., Chem. Commun., 1992, 319 DOI: 10.1039/C39920000319
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