The copper-promoted cycloaddition between nitrogen heterocyclic compounds (pyridine-2-carbonitrile, 2-pyridylacetonitrile and isoquinoline-3-carbonitrile) and ketones (acetone, pentan-2-one and pentan-3-one) has been studied, and a mechanism proposed on the basis of single crystal X-ray analysis, and 1H NMR and IR spectra of intermediate products.
M. Munakata, S. Kitagawa and T. Emori, J. Chem. Soc., Chem. Commun., 1991, 1244 DOI: 10.1039/C39910001244
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