Issue 13, 1991

Intramolecular alkyllithium additions to lactams; a synthesis of 2,3,9,9a-tetrahydro-1H-pyrrolo[1,2-a]indoles (pyrrolo[1,2-a]indolemnes) related to mitomycins

Abstract

Cyclisation of 5, 8, 10a and 10bvia their lithium derivatives followed by in situ reduction with lithium aluminium hydride gives pyrroloindolenines 2 and 9 and pyridinoindolenines 11a and 11b, respectively.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1991, 892-893

Intramolecular alkyllithium additions to lactams; a synthesis of 2,3,9,9a-tetrahydro-1H-pyrrolo[1,2-a]indoles (pyrrolo[1,2-a]indolemnes) related to mitomycins

J. M. D. Storey, C. McCarthy and K. Jones, J. Chem. Soc., Chem. Commun., 1991, 892 DOI: 10.1039/C39910000892

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