Some aldol condensation reactions proceeded more efficiently and stereoselectively in the absence of solvent than in solution. When the aldol reaction was carried in an inclusion complex with an optically active host compound, diastereo- and enantio-selective reaction occurred.
F. Toda, K. Tanaka and K. Hamai, J. Chem. Soc., Perkin Trans. 1, 1990, 3207 DOI: 10.1039/P19900003207
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