A new approach to the title ring system, required for the development of potential aromatase inhibitors, is described; acid chlorides (6) and (12) undergo an unusual addition–cyclisation reaction with alkynes, catalysed by aluminium chloride, to yield tricyclospirodienones (7) and (13).
F. T. Boyle, Z. S. Matusiak, O. Hares and D. A. Whiting, J. Chem. Soc., Chem. Commun., 1990, 518 DOI: 10.1039/C39900000518
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