β-Amido sulphoxides (2) react with the O-silylated ketene acetal (3) to give the 4-phenylthioazetidin-2-ones (4), which are converted into azetidin-2-one esters (5), known precursors of various types of carbapenem antibiotics.
Y. Kita, O. Tamura, N. Shibata and T. Miki, J. Chem. Soc., Perkin Trans. 1, 1989, 1862 DOI: 10.1039/P19890001862
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