The title β-lactam (6) is prepared in three steps from commercially available 2-azetidinone (9)(50% overall yield) and can be efficiently alkylated with a variety of electrophiles.
R. E. Dolle, M. J. Hughes, C. Li and L. I. Kruse, J. Chem. Soc., Chem. Commun., 1989, 1448 DOI: 10.1039/C39890001448
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