Issue 2, 1989
From the journal:

Journal of the Chemical Society, Chemical Communications

The α-bromoester-imine condensation promoted by zinc-trimethylchlorosilane: a stereospecific short formal synthesis of (±)-carbapenem antibiotics and related compounds

Fernando P. Cossío,   José M. Odriozola,   Mikel Oiarbide  and  Claudio Palomo  

Abstract

Ethyl bromoacetate reacts with imines in the presence of zinc activated by trimethylchlorosilane to give high yields of 3-unsubstituted β-lactams.

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Article information

DOI
https://doi.org/10.1039/C39890000074
Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 74-76

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The α-bromoester-imine condensation promoted by zinc-trimethylchlorosilane: a stereospecific short formal synthesis of (±)-carbapenem antibiotics and related compounds

F. P. Cossío, J. M. Odriozola, M. Oiarbide and C. Palomo, J. Chem. Soc., Chem. Commun., 1989, 74 DOI: 10.1039/C39890000074

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