2-Morpholinobuta-1,3-diene cycloadds to aromatic aldehydes, N-benzylideneaniline, and methyl vinyl ketone, to give oxan-4-ones, 4-morpholinotetrahydropyridines, and 4-acetyl-1-morpholinocyclohexene derivatives, respectively, with a high degree of diastereoselectivity.
J. Barluenga, F. Aznar, M. Cabal, F. H. Cano and M. de la Concepción Foces-Foces, J. Chem. Soc., Chem. Commun., 1988, 1247 DOI: 10.1039/C39880001247
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