Synthesis of 12-oxophytodienoic acid (12-oxoPDA), metabolic parent of OPC-compounds and epi-jasmonic acid
Abstract
The first synthesis of (±)-12-oxophytodienoic acid, a compound widely distributed in plants, and the metabolic parent of OPC compounds including epi-jasmonic acid, is described; whilst structurally resembling prostaglandin PGA1, it belongs to the cis-series not found in mammals.