Issue 8, 1988

Facile one-pot transformation of carboxylic acid chlorides into 2-substituted allyl alcohols

Abstract

The reaction of carboxylic acid chlorides (1) with chloromethyl-lithium generated in situ(1 : 2 molar ratio) in the presence of lithium iodide leads, after hydrolysis, to the corresponding homologated 2-substituted allyl alcohols (2).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 536-537

Facile one-pot transformation of carboxylic acid chlorides into 2-substituted allyl alcohols

J. Barluenga, J. M. Concellón, J. L. Fernández-Simón and M. Yus, J. Chem. Soc., Chem. Commun., 1988, 536 DOI: 10.1039/C39880000536

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