Issue 3, 1988

A short and efficient synthesis of a key intermediate for maytansinoid construction

Abstract

The cyclic carbamate (3), a key intermediate for our projected synthesis of trenudine (2), has been synthesised from 3,4-epoxycyclohexene (4) with ozonolytic cleavage of the cyclopentene (7) as a key step.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 217-218

A short and efficient synthesis of a key intermediate for maytansinoid construction

D. M. Hodgson, P. J. Parsons and P. A. Stones, J. Chem. Soc., Chem. Commun., 1988, 217 DOI: 10.1039/C39880000217

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