Issue 23, 1986

Asymmetric intramolecular conjugate addition of amines to chiral vinyl sulphoximides. Total synthesis of (R)-(+)- and (S)-(–)-carnegine

Abstract

The chiral vinyl sulphoximides (3a) and (3b) upon treatment with base, undergo cyclization to give chiral isoquinolines which were converted in to (R)-(+) and (S)-(–)-Carnegine.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1986, 1686-1687

Asymmetric intramolecular conjugate addition of amines to chiral vinyl sulphoximides. Total synthesis of (R)-(+)- and (S)-(–)-carnegine

S. G. Pyne, J. Chem. Soc., Chem. Commun., 1986, 1686 DOI: 10.1039/C39860001686

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