Issue 9, 1985

Aqueous solutions containing amino acids and peptides. Part 16.—Solute–solute interactions in solutions containing some N-acetyl-N′-methylamino acid amides

Abstract

The energetics of the interactions occurring between some N-acetyl-N′methylamino acid amides in aqueous solutions at 25 °C have been investigated. Osmotic coefficients and enthalpies of dilution have been obtained for single-component and two-component solute systems for the species N-acetyl-N′-methylglycinamide, N-acetyl-N′-methyl-L-alaninamide and N-acetyl-N′-methyl-L-leucinamide. Enthalpy-of-dilution data were also obtained for the sparingly soluble substance N-acetylglycyl-L-alaninamide. The results obtained have been used to calculate the pairwise free energy and enthalpy coefficients for the homotactic and heterotactic interactions and these are compared with results obtained earlier on some analogous systems containing the primary amino acid amides. A group-additivity approach has been used to rationalise the information obtained. This works tolerably well for most of the systems investigated.

Article information

Article type
Paper

J. Chem. Soc., Faraday Trans. 1, 1985,81, 2191-2205

Aqueous solutions containing amino acids and peptides. Part 16.—Solute–solute interactions in solutions containing some N-acetyl-N′-methylamino acid amides

G. M. Blackburn, T. H. Lilley and P. J. Milburn, J. Chem. Soc., Faraday Trans. 1, 1985, 81, 2191 DOI: 10.1039/F19858102191

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements