Co-operative and competitive hydrogen bonding in sucrose determined by SIMPLE 1H n.m.r. spectroscopy

Abstract

SIMPLE¹H n.m.r. measurements of isotope-shifted resonance for hydroxy groups in sucrose show that hydrogen bonding in solution is different from that observed in the solid state ^viz. there are two inter-residue hydrogen bonds in competition for one acceptor group (^i.e. OH1′⋯ O2 vs.OH3′⋯ O2) and an intramolecular hydrogen-bond network that is nucleated by the inter-residue hydrogen bonds.