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Pancratium littorale Jacq. Collected in Hawaii has beenfound to produce a new phenanthridone, pancratistatin, that significantly inhibits growth of the murine P388 lymphocytic leukaemia; an X-ray crystal structure determination of pancratistatin monomethyl ether (1c) was employed to assign structure (1a) to pancratistatin.
G. R. Pettit, V. Gaddamidi, G. M. Cragg, D. L. Herald and Y. Sagawa, J. Chem. Soc., Chem. Commun., 1984, 1693 DOI: 10.1039/C39840001693
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