Issue 1, 1984

High diastereoselectivity in the reaction of α-aminonitriles bearing an (S)-(+)-2-methoxymethylpyrrolidine group with Grignard reagents

Abstract

(S)-(+)-2-Methoxymethylpyrrolidine induces high diastereoselectivities (80% diastereoisomeric excess) in the reaction of α-aminonitriles with Grignard reagents.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1984, 40-41

High diastereoselectivity in the reaction of α-aminonitriles bearing an (S)-(+)-2-methoxymethylpyrrolidine group with Grignard reagents

N. Maigrot, J. Mazaleyrat and Z. Welvart, J. Chem. Soc., Chem. Commun., 1984, 40 DOI: 10.1039/C39840000040

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