Issue 0, 1983

Synthesis of the drimane-related sesquiterpenes euryfuran, confertifolin, and valdiviolide

Abstract

trans-3,4,4a,5,6,7,8,8a-Octahydro-5,5,8a-trimethylnaphthalene-1 (2H)-one (1) was converted into the drimane sesquiterpene euryfuran (5) in 59% yield. Euryfuran was then used as a starting material for the synthesis of two other drimane natural products, confertifolin and valdiviolide. The preparation of valdiviolide constitutes the first total synthesis of this molecule.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1983, 1379-1381

Synthesis of the drimane-related sesquiterpenes euryfuran, confertifolin, and valdiviolide

S. V. Ley and M. Mahon, J. Chem. Soc., Perkin Trans. 1, 1983, 1379 DOI: 10.1039/P19830001379

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