Rearrangement of an isothiazolidinone to a β-lactam. A model for penicillin biosynthesis
Abstract
Based on novel syntheses of a β-lactam from an isothiazolidinone, a mechanism of formation of the β-lactam ring in penicillin biosynthesis is proposed.
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Article information
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- Paper
J. Chem. Soc., Chem. Commun., 1983, 1349-1350
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Rearrangement of an isothiazolidinone to a β-lactam. A model for penicillin biosynthesis
C. J. Easton, J. Chem. Soc., Chem. Commun., 1983, 1349 DOI: 10.1039/C39830001349
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