The norbornadiene route to prostaglandin I2 and other prostaglandins: preparation and rearrangement of 7-substituted norbornadienes
Abstract
The cyclopentenylacetaldehyde (1) required for the synthesis of prostacyclin (prostaglandin I2) and other prostanoids is now readily available from the preparation and rearrangement of 7-substituted norbornadienes.