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Issue 8, 1983
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Asymmetric reduction of aromatic ketones with the reagent prepared from (S)-(–)-2-amino-3-methyl-1,1-diphenylbutan-1-ol and borane

Abstract

Asymmetric reduction of prochiral aromatic ketones with the reagent prepared from (S)-(–)-2-amino-3-methyl-1,1-diphenylbutan-1-ol [(S)-(1)] and borane afforded the corresponding aromatic secondary alcohols in high optical (94–100% enantiomeric excess) and chemical (100%) yields.

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Article type: Paper
DOI: 10.1039/C39830000469
Citation: J. Chem. Soc., Chem. Commun., 1983,0, 469-470

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    Asymmetric reduction of aromatic ketones with the reagent prepared from (S)-(–)-2-amino-3-methyl-1,1-diphenylbutan-1-ol and borane

    S. Itsuno, K. Ito, A. Hirao and S. Nakahama, J. Chem. Soc., Chem. Commun., 1983, 0, 469
    DOI: 10.1039/C39830000469

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