Issue 8, 1983

Asymmetric reduction of aromatic ketones with the reagent prepared from (S)-(–)-2-amino-3-methyl-1,1-diphenylbutan-1-ol and borane

Abstract

Asymmetric reduction of prochiral aromatic ketones with the reagent prepared from (S)-(–)-2-amino-3-methyl-1,1-diphenylbutan-1-ol [(S)-(1)] and borane afforded the corresponding aromatic secondary alcohols in high optical (94–100% enantiomeric excess) and chemical (100%) yields.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1983, 469-470

Asymmetric reduction of aromatic ketones with the reagent prepared from (S)-(–)-2-amino-3-methyl-1,1-diphenylbutan-1-ol and borane

S. Itsuno, K. Ito, A. Hirao and S. Nakahama, J. Chem. Soc., Chem. Commun., 1983, 469 DOI: 10.1039/C39830000469

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