A general synthesis of α-fluorovinylphosphonates result from Wadsworth–Emmons condensation of tetra-alkyl fluoromethylenebisphosphonates with aldehydes and ketones with stereoselectivity favouring the less hindered product which can be reduced to give α-fluorophosphonates in good yield.
G. M. Blackburn and M. J. Parratt, J. Chem. Soc., Chem. Commun., 1982, 1270 DOI: 10.1039/C39820001270
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