Stereochemistry of the coenzyme B12-mediated rearrangement of 2-aminoethan-1-ol by ethanolamine ammonia-lyase
Abstract
Reaction kinetics and 2H n.m.r. spectra of reaction products show independently that the coenzyme B12-mediated rearrangement of 2-aminoethan-1-ol by the enzyme ethanolamine ammonia-lyase proceeds with migration of the (1S)-hydrogen.