Treatment of 5-(methylamino)-1-β-D-ribofuranosylimidazole-4-carboxamide (3) with CNBr followed by cyclization and reaction with bromoacetone gave 3-β-D-ribofuranosylwye (2) whose glycosidic bond was cleaved rapidly in acidic or alkaline solution, but was fairly stable at pH 5–8·5 at 37 °C.
T. Itaya, T. Watanabe and H. Matsumoto, J. Chem. Soc., Chem. Commun., 1980, 1158 DOI: 10.1039/C39800001158
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