Issue 10, 1980

Molecular conformation of thyrotropin-releasing hormone from the X-ray structural analysis of its tartrate

Abstract

An X-ray crystal study of thyrotropin-releasing hormone tartrate has revealed that its molecular structure, in contrast with predictions based on energy calculations and n.m.r. spectroscopic studies, contains an extended peptide bond stabilized by a hydrogen bond between the π-NH unit of histidine and the carbonyl oxygen of the proline amide.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1980, 438-439

Molecular conformation of thyrotropin-releasing hormone from the X-ray structural analysis of its tartrate

K. Kamiya, M. Takamoto, Y. Wada, M. Fujino and M. Nishikawa, J. Chem. Soc., Chem. Commun., 1980, 438 DOI: 10.1039/C39800000438

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