High-pressure cycloaddition of 2(1H)-pyridones with dimethyl acetylenedicarboxylate
Abstract
Reaction of dimethyl acetylenedicarboxylate with the 2(1H)-pyridones (1) at 10–15 kbar pressure and 60–70 °C gives the bicyclic adducts (2), some of which are unobtainable under atmospheric pressure in moderate yields.