Issue 16, 1979

Synthesis of 9-deoxa-9,10-dehydroprostaglandin-D2 through reaction of 2-oxatricyclo[3.3.0.04,6]oct-7-en-3-one with a cuprate reagent

Abstract

The prostanoid (10) has been prepared by reaction of the tricyclic lactone (4) with the cuprate reagent (12) to give the acid (5) and subsequent Cope rearrangement of the related aldehyde (6).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1979, 679-680

Synthesis of 9-deoxa-9,10-dehydroprostaglandin-D2 through reaction of 2-oxatricyclo[3.3.0.04,6]oct-7-en-3-one with a cuprate reagent

S. M. Ali, M. A. W. Finch, S. M. Roberts and R. F. Newton, J. Chem. Soc., Chem. Commun., 1979, 679 DOI: 10.1039/C39790000679

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