The diazoketones (3a and b) and the iminomalonates (7a and b) have been converted into the tetracyclic vinylogous amides (6a and b) by an acid-catalysed single-step reaction; Birch reduction of the amides (6a and b) afforded the corresponding tetracyclic ketones (2a and b), synthons for the synthesis of functionalized aspidosperma alkaloids.
S. Takano, K. Shishido, M. Sato, K. Yuta and K. Ogasawara, J. Chem. Soc., Chem. Commun., 1978, 943 DOI: 10.1039/C39780000943
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