Synthesis of the diastereoisomers of S-(2-carboxypropyl)-L-cysteine and their S-mono- and SS-di-oxides
Abstract
Addition of L-cysteine to methacrylamide followed by fractional crystallization yielded (+)- and (–)-S-(2-carbamoylpropyl)-L-cysteine, acidic hydrolysis of which gave the corresponding acids. These were converted into the corresponding two N-2,4-dinitrophenyl derivatives, two SS-dioxides, and four S-mono-oxtdes.