A short synthesis of the tetrapyrrole pigment precursor porphobilinogen (1) has been developed which requires only readily available and inexpensive starting materials, and which is amenable to introduction of isotopic labels at key positions required for biosynthetic studies.
M. I. Jones, C. Froussios and D. A. Evans, J. Chem. Soc., Chem. Commun., 1976, 472 DOI: 10.1039/C39760000472
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