Issue 9, 1975

Binding of 7,12-dimethylbenz[α]anthracene to DNA investigated by tritium displacement

Abstract

7,12-Dimethylbenz[α]anthracene, specifically labelled with tritium in the 7-methyl group, has been prepared and then bound covalently to DNA both photochemically in vitro and metabolically in vivo; a significant proportion of the tritium is displaced in both cases.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1975, 358-359

Binding of 7,12-dimethylbenz[α]anthracene to DNA investigated by tritium displacement

G. M. Blackburn, A. J. Flavell, P. E. Taussig and J. P. Will, J. Chem. Soc., Chem. Commun., 1975, 358 DOI: 10.1039/C39750000358

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