Nitro-heteroaromatic derivatives of amino-acids and peptides. Part III. Application of ultraviolet–visible absorption and circular dichroism to N-(3-nitro-2-pyridyl)amino-acids

Abstract

U.v.–visible absorption and c.d. curves have been recorded for N-(3-nitro-2-pyridyl)amino-acids and compared with those of related compounds. The chiroptical properties of these compounds, along with the chemical behaviour of 2-fluoro-3-nitropyridine, suggest a novel procedure for determining the absolute configuration of N-terminal amino-acids of peptides.