Microbiological hydroxylation of steroids. Part III. A convenient, microbiological route to 15-oxygenated 5α-androstanes.
Abstract
By utilising the specific hydroxylating capabilities of the fungi Aspergillus ochraceus Wilhelm and Penicillium urticae Bain in combination with standard chemical reactions, 5α-androstan-15α-ol has been obtained from 3α-hydroxy-5α-androstan-17-one in an overall yield of 16%.