The kinetics and mechanism of the electrophilic substitution of heteroaromatic compounds. Part XXV. The acid-catalysed hydrogen-exchange of some 2-aminopyridine derivatives
Abstract
Rate profiles are reported for hydrogen exchange at the 3-position for 2-amino-5-chloropyridine, 5-chloro-2-dimethylaminopyridine, and 2-amino-5-bromopyridine 1-oxide and for exchange at the 5-position for 2-amino-3-methylpyridine.