An infrared study of solvent effects on the carbonyl stretching bands of some androgen esters

Abstract

The solvent effects of chloroform, benzene, and carbon tetrachloride on the carbonyl stretching bands of six 17β-acyl-oxyandrost-4-en-3-ones (testosterone esters) and 17β-propionyloxy-5α-androstan-3-one (androstanolone propionate) are recorded. In the solute–solvent interactions responsible for the spectral changes, the carbonyl group is considered to be the electron donor and particular attention is directed towards the mode of interaction with benzene and carbon tetrachloride. The changes in a composite band are considered as the integrated modifications of component sub-bands; some of which are resolved and assigned. Also the reasons for the split peak in the conjugated ketone are reviewed.