The administration of [1-14C]acetate to Dioscorea hispida plants resulted in the formation of radioactive dioscorine (0·2% incorporation), the pattern of labelling being consistent with the hypothesis that this alkaloid is formed from four acetate units and a piperidine moiety which may be derived from lysine.
E. Leete, A. R. Pinder, I. Hargittai and K. Hedberg, J. Chem. Soc. D, 1971, 1499 DOI: 10.1039/C29710001499
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