Issue 21, 1970

Steric course of the 3-hydroxy-3-methylglutaryl CoA reductase reaction

Abstract

Reduction of the hemithioacetal from coenzyme A and (±)-mevaldic acid with (4R)-[4-3H]-NADPH in the presence of 3-hydroxy-3-methylglutaryl CoA reductase from yeast gives (3R,5S)-[5-3H]-mevalonic acid.

Article information

Article type
Paper

J. Chem. Soc. D, 1970, 1394a-1394a

Steric course of the 3-hydroxy-3-methylglutaryl CoA reductase reaction

P. Blattmann and J. Rétey, J. Chem. Soc. D, 1970, 1394a DOI: 10.1039/C2970001394A

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