Absolute configuration of pulvilloric acid
Abstract
The asymmetric carbon atom in (+)-pulvilloric acid has been shown to have the S-configuration by measurement of the circular dichroism of the methyl xanthate ester of (–)-1-(3,5-dimethoxyphenyl)heptan-2-ol, a degradation product of the acid. The R-configuration of the corresponding asymmetric carbon atom in (–)-citrinin has been confirmed in a similar way. The n.m.r. spectrum of pulvilloric acid is recorded.