Issue 0, 1967

Synthetic studies of nucleic acids on polymer supports. Part I. Oligodeoxyribonucleotide synthesis on an insoluble polymer support

Abstract

The synthesis of thymidylyl-(5′ 3′)-thymidylyl-(5′ 3′)-thymidine 5′-phosphate using an insoluble polystyrene support is described. The first nucleotide is attached to the polymer by a phosphoramidate linkage which is cleaved by mild acid treatment to release the product.

Article information

Article type
Paper

J. Chem. Soc. C, 1967, 2438-2442

Synthetic studies of nucleic acids on polymer supports. Part I. Oligodeoxyribonucleotide synthesis on an insoluble polymer support

G. M. Blackburn, M. J. Brown and M. R. Harris, J. Chem. Soc. C, 1967, 2438 DOI: 10.1039/J39670002438

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