The synthesis and aggregation of 9-phenyl- and 9-s-butyl-3,6-bisdimethylaminoacridine in solution. The dealkylation of 9-t-butylacridans

Abstract

9-Butyl-(Id) and 9-phenyl-3,6-bisdimethylaminoacridan (If) have been synthesised and oxidised to their aromatic analogues (IIc) and (IId). 3,6-Bisdimethylamino-9-t-butylacridan (Ie) and 9-t-butylacridan (Ib) undergo oxidative dealkylation in the 9-position when treated with various oxidising agents. The absorption and fluorescence spectra of the two 9-substituted 3,6-bisdimethylaminoacridines have been examined and compared with that of 3,6-bisdimethylaminoacridine under a variety of conditions, and the binding of these three dyes to inorganic polyphosphate at various polymer–dye ratios has been examined spectroscopically.