Applications of sulfuryl fluoride (SO2F2) in chemical transformations

Abstract

A number of novel methodologies concerning the chemical, biological and medicinal applications of sulfuryl fluoride (SO₂F₂) gas have dramatically improved year by year. SO₂F₂ is a cheap, abundant and relatively inert electrophile, and also has been widely used as a fumigant for over five decades. Recently, it has gained significant attention as a reagent in organic synthesis. Herein, we summarize chemical transformations using the readily available feedstock SO₂F₂ gas.