NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid

Hong-Guen Lee; Na-Kyeong Hong; Young-Tae Chang

doi:10.1039/D3CC02501B

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NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid†

Hong-Guen Lee,^a Na-Kyeong Hong^a and Young-Tae Chang

*^a

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* Corresponding authors

^a Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea
E-mail: ytchang@postech.ac.kr

Abstract

The fluorescent probe pair, NBD-B2 and Styryl-51F, selectively detects NMN over citric acid. NBD-B2 exhibits increased fluorescence, while Styryl-51F shows decreased fluorescence upon NMN addition. Their ratiometric fluorescence change enables highly sensitive and wide-range detection of NMN, effectively distinguishing it not only from citric acid but also other NAD boosters.

This article is part of the themed collection: Chemosensors and Molecular Logic

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Article information

DOI: https://doi.org/10.1039/D3CC02501B
Article type: Communication
Submitted: 24 May 2023
Accepted: 03 Jul 2023
First published: 04 Jul 2023

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Chem. Commun., 2023,59, 9372-9375

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NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid

H. Lee, N. Hong and Y. Chang, Chem. Commun., 2023, 59, 9372 DOI: 10.1039/D3CC02501B

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Chemical Communications

NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid†

Abstract

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NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid

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